A Complete Insight Into CBDA

There are so many cannabinoids out there (psychoactive and non-psychoactive) that it can be hard for a newbie in particular to keep track of. However, one cannabinoid that’s making some positive waves is cannabidiolic acid (CBDA). And today, we are going to provide an awesome overview of what to expect from CBDA.

What is CBDA?

CBDA, or cannabidiolic acid, is a compound found in the cannabis plant. It's a precursor to CBD (cannabidiol), one of the more well-known cannabinoids. CBDA is present in the raw cannabis plant and converts to CBD through a process called, “decarboxylation”, which typically occurs through heating or aging. Like CBD, CBDA does not produce psychoactive effects, meaning it doesn't cause the "high" associated with THC, another cannabinoid found in cannabis.

What is CBDA’s History?

CBDA has gained attention for its potential therapeutic properties – more on that in a little bit here, but its history is closely intertwined with the broader history of cannabis.

Here's a brief overview of the history of CBDA:

• Ancient Use: Cannabis has been used for medicinal and recreational purposes for thousands of years. Ancient civilizations in various parts of the world, including China and India, were using cannabis for its therapeutic properties long before the discovery of specific cannabinoids like CBDA.
• Discovery of Cannabinoids: The isolation and identification of individual cannabinoids, including CBDA, began in the mid-20th century. In 1963, Dr. Raphael Mechoulam and his colleagues in Israel successfully isolated CBDA from the cannabis plant. This groundbreaking work marked the beginning of our understanding of the chemical composition of cannabis.
• Acidic Precursor: CBDA is the acidic precursor to CBD. When the cannabis plant grows, it produces CBDA in its trichomes, which are small, resinous glands found on the surface of the plant. Through a process called decarboxylation, CBDA can be converted into CBD when exposed to heat or light.
• Research and Interest: Research into the potential medicinal properties of CBDA has grown in recent years. Like CBD, CBDA is non-psychoactive and does not produce the "high" associated with THC (tetrahydrocannabinol). Some studies have suggested that CBDA may have anti-inflammatory, anti-nausea, and anti-anxiety effects, although more research is needed to fully understand its potential benefits.
• Legal Status: The legal status of CBDA varies from country to country and state to state within the United States. In some places, CBDA is considered a controlled substance, while in others, it may be legally available for medical or recreational use.
• Commercial Products: As interest in CBDA and other cannabinoids has grown, various cannabis and hemp-derived products containing CBDA have become available on the market. These products often include CBDA in addition to other cannabinoids, such as CBD, and are marketed for a range of potential health benefits.

Is CBDA Actually Legalized in the United States?

CBDA is a legal cannabinoid under federal law because of the 2018 Farm Bill. This piece of legislation essentially allowed for all hemp derivatives, excluding delta 9 THC, to be legal. Also, CBDA is not banned in any states, since it’s non-intoxicating.

Can CBDA Get You High?

CBDA is not psychoactive. Even decarboxylated, CBD is not intoxicating as it has no psychoactive properties, and raw cannabinoids in general don’t act on CB1 receptors that cause us to get high, as you saw with THCA, above.

What are the Potential Benefits of CBDA?

CBDA has been studied less extensively than CBD, but emerging research suggests it may have its own unique properties and potential health benefits. However, more research is needed to fully understand its effects and potential therapeutic uses. In the meantime, here’s what we know:

• Serotonin Uptake: CBDA works closely with 5-ht receptors, which influence our serotonin levels. Serotonin is the neurotransmitter that regulates our mood, sleep cycle, sexual function, metabolism and energy levels, and even plays a role in appetite. Low serotonin is associated with depressive disorders and other mental health dysfunctions. CBD also works on these receptors, but CBDA’s effects seem to be significantly more potent. Because of its influence on 5-ht receptors, it may also reduce nausea.
• Anti-Inflammatory Properties: CBDA has the impressive ability to regulate inflammation by inhibiting COX-2, the enzyme that precedes the body’s inflammatory response. Studies show that CBDA’s effects on inflammation may be quite powerful and comparable to those of NSAIDs.
• Influence on SARS-CoV-2: In early 2022, a study was published that found that when taken with CBGA, CBDA was able to prevent SARS-CoV-2 from entering the cells of the lungs and other organs. CBDA and CBGA bind to the spike protein of the virus to change its external structure, which prevents it from making its way into the organs of the body where it can cause the virus to become much more lethal.

What are the potential Side Effects of CBDA?

While CBDA is believed to have therapeutic potential, keep in mind there could be some side effects, and this is determined by several variables, including the dosage, individual sensitivity, and interactions with other medications or substances. These can be the following:

• Dry Mouth
• Dizziness
• Changes in Appetite
• Diarrhea
• Changes in Mood or Alertness

CBDA Dosing and Product Types

If you decide that CBDA is suitable for you (after also having a talk with your doctor), it's important to start with a low dose and gradually increase it until you achieve the desired effect. This approach helps minimize the risk of adverse effects. CBDA can be found in various forms (high or lower amounts), including tinctures, capsules, topicals, vapes, and even flower. The appropriate dosing method may depend on the form you choose.

Also, some other advice you should follow:

1. Follow Product Instructions: Always follow the dosing instructions provided on the product label. Manufacturers typically provide recommended dosages for their specific products.
2. Pay Attention to Concentration: CBDA products can vary in concentration. Be aware of the concentration of CBDA in the product you're using, as this will affect your dosing. Higher concentrations may require smaller doses.
3. Monitor Effects: After taking CBDA, pay close attention to how it affects you. Keep track of any changes in your symptoms and overall well-being. This information can help you and your healthcare professional adjust your dosage as needed.
4. Individual Factors: Dosing can vary significantly from person to person based on factors such as body weight, metabolism, tolerance, and the specific medical condition being treated. What works for one person may not be appropriate for another.
5. Be Patient: It may take some time to find the right CBDA dosage that works best for you. Be patient and give your body time to adjust to the compound.