Best 2024 Cannabinoids for Nausea or an Upset Stomach

Digestive complaints happen to all of us, whether they be that unpleasant sensation of nausea, or the pain of an upset stomach. And, of course, when we’re in the midst of them, the only thing on our minds is finding relief, fast. Sure, there are plenty of ways to relieve digestive symptoms like gas, bloating, indigestion, and nausea, ranging from all-natural herbs to prescription medications.

However, we are witnessing more people who deal with frequent digestive symptoms, turning toward cannabinoids located in the hemp plant. Cannabinoids are the cannabis-derived compounds that interact with our body’s endocannabinoid system (ECS) in order to regulate physiological processes, including overall digestive function.

Now, as you might have guessed, some cannabinoids are better suited for tummy troubles than others. That’s why we’re gonna cover our favorite picks for digestive discomfort - in particular, nausea or an upset stomach.

The Truth About Digestive Ailments

In reality, we’re all going to get digestive symptoms from time to time, including both nausea and upset stomach. And, these symptoms can exist on their own or in combination with one another depending on the culprit. There are countless reasons for digestive discomfort, ranging from eating something that just doesn’t agree with us, to a serious infection or digestive disorder. Regardless of the cause, relief is essential, as nausea and an upset stomach can really interfere with our ability to get much accomplished at all.

Of course, if you’re prone to frequent bouts of upset stomach or nausea, it’s very important that you seek the attention of a medical professional. While most instances are quite benign, sometimes, these symptoms can indicate a deeper and more serious issue. Besides that, a professional medical professional can help identify the underlying cause, and then address the problem at its root.

At the same time, there is nothing wrong with opting for some fast relief in the meantime. Not to mention, there are plenty of treatment options out there, although we’re seeing a clear trend toward seeking out the cannabinoids in the hemp plant. The cannabinoids in hemp have been shown in research to provide all kinds of potential benefits through its relationship to the ECS. These plant compounds are so potentially helpful that many states list digestive ailments as qualifying conditions for medical marijuana.

Which Cannabinoids Can Help the Most with Nausea and Upset Stomach?

If nausea and upset stomach are what ail you, we’ve got you covered. Again, there are over 100 cannabinoids in the hemp plant, and each one offers a unique chemical structure that determines how effectively it attaches to specific cannabinoid receptors. Essentially, this means that each cannabinoid has dominant effects, some of which happen to be related to our digestive functions.

Best Cannabinoid for Nausea and Upset Stomach #8: CBDA

What CBDA is: CBDA is a non-psychoactive compound that serves as a precursor to CBD. More specifically, CBDA is decarboxylated to create CBD, meaning it is heated. This can happen instantly if smoked or vaped, or slowly if the plant material is left to dry in the sun, or even at room temperature. Cannabidiolic acid can, therefore, be thought of as raw CBD. CBDA is most often found in the live or raw hemp plants bred for high CBD levels. CBDA has been shown to inhibit the production of cyclooxygenase-2 (COX-2) enzymes. While CBDA doesn't directly bind to CB1 or CB2 receptors in the same way that THC does, it may indirectly influence the endocannabinoid system. Research suggests that CBDA may interact with other receptors and enzymes in the ECS, potentially modulating the effects of other cannabinoids.

Why CBDA Can Help: Research on CBDA is still in its early stages, but it may have potential anti-inflammatory, anti-nausea, and anti-anxiety properties. Some studies suggest it could be useful for conditions like epilepsy and cancer.

CBDA Product Recommendation: Farma Barn CBDA Isolate Lemon Flavored Tincture. This amazing formula is free of harsh additives, and it goes directly under the tongue for quick and long-lasting potential relief. Plus, the lemon flavor adds some wonderful bliss to it.

Best Cannabinoid for Nausea and Upset Stomach #7: Delta 8 THC

What Delta 8 THC is: Delta 8 THC is a minor cannabinoid found in cannabis, which comes from oxidized delta 9 THC. A tiny amount of delta 9 THC converts into delta 8 THC as the plant ages, resulting in an entirely new chemical structure. Delta 8 is 30% less intoxicating than delta 9, and the cannabinoid has a strong affinity for CB1 receptors which regulate nervous system functions. Initially discovered in the 1960s, delta 8 has a surprising amount of research behind it to demonstrate real potential therapeutic value.

Why Delta 8 THC Can Help: Delta 8 THC possesses clear anti-inflammatory qualities that can make it super useful against inflammation-based digestive discomfort. Simultaneously, like many cannabinoids, it’s known for its antiemetic qualities that can reduce nausea.

Delta 8 THC Product Recommendation: Hemplitude Delta 8 THC Live Rosin Vape Cartridge. This 510-threaded vape cart comes fitted with ceramic coils that heat the oil to the perfect temperature for a smooth flavorful pull. This also helps elongate the life span of your tank. Other features include food-grade silicone and specialized borosilicate glass to give you the unbeatable quality you deserve. Best of all, it combines delta 8 distillate with high-potency live rosin, rich in terpenes, and comes in some pretty excellent strains that can provide noticeable relief.

Best Cannabinoid for Nausea and Upset Stomach #6: HHC

What HHC is: Hexahydrocannabinol (HHC) is a naturally occurring analog of delta 9 THC. In fact, it’s believed that HHC and delta 9 THC share an identical chemical structure, except the former has an added hydrogen atom that influences its chemical stability. Basically, HHC is considered the only naturally occurring cannabinoid that behaves exactly like delta 9 THC, which is why it’s immensely popular. Since HHC was only discovered fairly recently, research on it is lacking.

Why HHC Can Help: There are no studies suggesting a link between HHC and digestive relief, however the similarities between delta 9 and HHC give us a lot of hope. Delta 9 THC has been found to supply serious relief from nausea, and can help with an upset stomach, especially if it’s caused by underlying inflammation of the digestive tract.

HHC Product Recommendation: ELYXR HHC Flower comes in some pretty tempting strains, all while being rich in HHC along with other cannabinoids and terpenes, for a holistic approach to your digestive wellness with only premium quality.

Best Cannabinoid for Nausea and Upset Stomach #5: THCP

What THCP is: Tetrahydrocannabiphorol (THCP) is naturally found in cannabis, and it was discovered back in 2019. THCP is the most potent cannabinoid in the plant, estimated to be 10x as strong as delta 9 THC, due to its enhanced carbon sidechain which allows it to attach to CB1 receptors (cannabinoid receptors in the brain) at up to 33x the rate of delta 9. Basically, THCP has been uncovered to have identical effects as delta 9, only much stronger.

Why THCP Can Help: There aren’t any studies on the role that THCP can have in digestive discomfort, but the study linked above shows that it has significant antiemetic properties, and major anti-inflammatory potential.

THCP Product Recommendation: iDELTAX THCP Vape Cartridge. This vape cartridge attaches to any 510-threaded vape pen, and it contains an ample amount of THCP that you can enjoy on demand for fast-acting and powerful effects as needed.

Best Cannabinoid for Nausea and Upset Stomach #4: CBG

What CBG is: Cannabigerol (CBG) is a nonintoxicating cannabinoid known as the “mother cannabinoid”, because it’s the first cannabinoid to develop in immature cannabis buds before splitting itself into over 100 new cannabinoids. CBG operates primarily on CB2 receptors, found in the immune and digestive systems, while also affecting cognitive functions and certain nervous system functions.

Why CBG Can Help: CBG has been shown in numerous studies to deliver notable relief to those dealing with all kinds of pain. The cannabinoid possesses powerful anti-inflammatory potential, and it also happens to prefer CB2 receptors, which are found along the digestive tract.

CBG Product Recommendation: BioWellness X CBG Oil with PCR Hemp Oil. This ultra-pure formula is free of harsh additives, and it goes right under the tongue for quick and long-lasting potential relief. Full Spectrum PCR Hemp Oil with 2000mg CBD + 1000mg CBG Oil Extract – hard to find a more potent Full Spectrum Oil than this.

Best Cannabinoid for Nausea and Upset Stomach #3: CBD

What CBD is: Cannabidiol (CBD) is the dominant cannabinoid in the hemp plant, and it’s nonintoxicating, which makes it a viable option for those seeking relief without any psychoactive effects. CBD is a cannabinoid that’s been studied at length since its discovery several decades ago, and it has been found to offer a substantial number of potential benefits.

Why CBD Can Help: Many studies point to positive results when taking CBD for nausea and upset stomach, as it works closely with cannabinoid receptors that regulate all kinds of digestive functions.

CBD Product Recommendation: Sunset Lake Hemp CBD Flower Pre-Rolls are housed in a 98mm Raw-brand hemp paper cone and packed with sun-grown Hemp Flower. So, being stuffed with fresh, CBD-rich hemp flower buds, these pre-rolls are easy to consume, and work quickly to get you relief in no time.

Best Cannabinoid for Nausea and Upset Stomach #2: THCA

What THCA is: Tetrahydrocannabinolic acid (THCA) is something of a misleading cannabinoid. THCA is the raw precursor to delta 9 THC, and it’s found in raw cannabis flower. When THCA is heated, it turns into delta 9 THC through a process called decarboxylation, which changes its chemical structure and enables it to attach to CB1 receptors to produce the THC effects we all know. THCA vapes, flower, and dabs may not be labeled as THC products, but when they’re used, the heat to which the THCA is exposed converts the cannabinoid into delta 9, meaning that you’re really just getting high off of delta 9 like you would if you were taking marijuana.

Why THCA Can Help: We’ve already gone over the positive effects of delta 9 THC on various digestive symptoms, and again, THCA products like vapes, flower, and dabs deliver the effects of delta 9 THC due to the heating process that they undergo.

THCA Product Recommendation: Binoid THCA Live Rosin 1G Disposable Vape Pen. This groundbreaking disposable vape utilizes premium 99% THCA distillate, combined with live rosin cannabis terpene strains, ensuring a superior experience compared to regular vapes, thus adding to the overall potential benefits.

Best Cannabinoid for Nausea and Upset Stomach #1: Delta 9 THC

What Delta 9 THC is: Delta 9 THC is the dominant chemical compound in marijuana, and it’s found in trace amounts in the hemp plant. Legally, hemp products must contain a maximum of 0.3% delta 9 THC per dry weight, so companies have had to get creative in order to create products that deliver an effective number of milligrams of THC. THC is also the most widely studied cannabinoid in history, and the reason why medical marijuana exists in the United States.

Why Delta 9 THC Can Help: We’ve already talked about the role that delta 9 can play in addressing various digestive symptoms, which is why this cannabinoid is the #1 go-to for nausea and upset stomach.

Delta 9 THC Product Recommendation: Wild Shroomz Delta 9 THC + Lion’s Mane Mushroom Gummies. Each gummy offers 250mg of their signature mushroom blend, coupled with 5mg delta 9 THC for a euphoric and blissful buzz. Combining the effects of pure delta 9 distillate with Lion’s Mane mushrooms provides even better results, as the latter ingredient is known for its positive effects on the body as well.

Say Goodbye to Your Digestive Troubles with Hemp!

Nausea and upset stomach are pretty common symptoms of digestive imbalance, and they can be anything from annoying to debilitating. At The Calm Leaf, you’ll find all kinds of cannabinoids and products, like the ones above, that have what it takes to provide notable relief. Explore our catalog, and simply enjoy the holistic properties of cannabis in all of their glory.